人黑色素细胞是神经嵴衍生细胞,位于人的某些器官,如皮肤、眼睛、内耳和软脑膜。黑色素细胞不能向这些器官的移动,可以解释先天性皮肤白斑(斑驳病)跟虹膜异色(不同颜色并置)之间的关系以及Waardenburg综合征的先天性耳聋。皮肤黑色素细胞合成并转运黑色素到周围的角质细胞,使皮肤有色素沉积以保护皮肤对抗阳光辐射。随着新的细胞培养技术和改良的培养方法,在成功培养这类细胞在纯种群时,发现了新型的黑色素细胞基因——msgl,它能编码一种与色素沉着相关的核蛋白。
人表皮黑色素细胞(浅色素)提取于人表皮组织,一代冻存。每管含有细胞数>5x10^5cells/ml,此细胞通过Fibronectin和NGF-receptor(p75)免疫荧光染色验证,经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。
推荐培养基:黑色素细胞培养基 (MeIM, Cat. #2201)
货号
|
2200
|
产地
|
美国
|
缩写
|
HEM-l
|
规格
|
5 x 10^5 /1ml
|
用途
|
科研
|
储存
|
液氮
|
运输
|
干冰
|
关键字
|
人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l 人表皮黑色素细胞-浅色素 HEM-l
|
公司简介
|
合肥星肽生物科技有限公司作为专业的ScienCell中国代理商,专业经营实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发。合肥星肽生物科技有限公司始终致力于为客户提供可靠的研究材料以及方便快捷的服务,对购买项目的前期资料提供,中期合同保证,后期货物跟踪到*终售后的确保项目准确到位,都有相关专业人士进行维护,确保您在合肥合肥星肽生物科技有限公司公司获得*上等服务!
|
联系方式
|
何经理,合肥星肽生物科技有限公司,Tel:0551-63802898 400-8702-898,
E-mail:info@qingbio.com http://www.qingbio.com QQ:514713116
|
1.) Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ."Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment." 2014 Jan;124(1):425-36. doi: 10.1172/JCI69404. Epub 2013 Dec 20.
2.) Yang J, Bill MA, Young GS, La Perle K, Landesman Y, Shacham S, Kauffman M, Senapedis W, Kashyap T, Saint-Martin JR, Kendra K, Lesinski GB. (2014) 'Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells.'
3.) Yang J, Bill MA, Young GS, La Perle K, Landesman Y, Shacham S, Kauffman M, Senapedis W, Kashyap T, Saint-Martin JR, Kendra K, Lesinski GB. (2014) "Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells." PloS one. 9: e102983.
4.) Li JL, Mazar J, Zhong C, Faulkner GJ, Govindarajan SS, Zhang Z,Dinger ME, Meredith G, Adams C, Zhang S, Mattick JS, Ray A, Perera RJ (2013) 'Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network.'
5.) Li JL, Mazar J, Zhong C, Faulkner GJ, Govindarajan SS, Zhang Z,Dinger ME, Meredith G, Adams C, Zhang S, Mattick JS, Ray A, Perera RJ (2013) "Genome-wide methylated CpG island profiles of melanoma cells reveal a melanoma coregulation network." . 3.
6.) Mazar J, DeYoung K, Khaitan D, Meister E, Almodovar A, Goydos J, Ray A, Perera RJ. (2010) "The regulation of miRNA-211 expression and its role in melanoma cell invasiveness." PLoS One. 5: e13779.
7.) Savaraj N, You M, Wu C, Wangpaichitr M, Kuo MT, Feun LG. (2010) "Arginine deprivation, autophagy, apoptosis (AAA) for the treatment of melanoma." Curr Mol Med. 10: 405-12.
8.) Doudican N, Rodriguez A, Osman I, Orlow SJ. (2008) "Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells." Mol Cancer Res. 6: 1308-15.
9.) Palmer MB, Majumder P, Green MR, Wade PA, Boss JM. (2007) "A 3' Enhancer Controls Snail Expression in Melanoma Cells." Cancer Res. 67: 6113-20.
10.) May KM, Vogt A, Bachas LG, Anderson KW. (2005) "Vascular endothelial growth factor as a biomarker for the early detection of cancer using a whole cell-based biosensor." Anal Bioanal Chem. 382: 1010-6.
There are no product questions yet.