Astrocytes are the most abundant cells in the central nervous system
(CNS). Astrocytes provide a variety of biological functions, such as
supporting endothelial cells involved in blood-brain barrier formation,
providing nutrients to neurons, maintaining extracellular ion balance,
and promoting repair in the CNS. Astrocyte conditioned medium (ACM) has
been widely used to support the growth of neurons and endothelial cells
in culture. ACM has also been shown to protect neurons from
corticosterone-induced damage.
Mouse ACM-57 is a liquid medium prepared from primary C57BL/6 mouse
astrocyte cultures by using astrocyte medium (Cat #1801) conditioned for
48 hours. The medium is sterile filtered and has a pH of 7.4 when
equilibrated in an incubator with an atmosphere of 5% CO2/95% air.
